
Meth is neurotoxic, meaning it causes permanent damage to the dopamine-producing neurons in the brain and leading to long-term changes in personality. They’re caused by the large amounts of dopamine released by meth usage and are similar to those observed in patients with Parkinson’s or obsessive-compulsive disorder.Īnd while meth creates a state of euphoria, its effects are much more sinister. This can take the shape of destructive behaviors, confusing or irrational patterns of speech, or sudden outbursts of anger and violence that can last for days after last using methamphetamine. Tweaking can refer to the nervous, repeated physical motions that meth users engage in or to the unpredictable mood swings and violent outbursts that accompany meth usage. “Tweaking” is a slang term for the compulsive, disorganized behavior that methamphetamine users exhibit, particularly after large doses or long periods of repeated dosing.

Dramatic Mood Swings or Unusual Periods of Depression

Strange or Destructive New Tics and Habits

